Executive member for regeneration and culture David Budd (Lab) said: "We don't think the people of Middlesbrough will agree with this verdict. In fact we are sure that the people who have visited the town, to see Middlesbrough Institute of Modern Art, for example, or enjoy Proms in the Park or its hospitality, will disagree quite vehemently.
"The fact is a whole range of factors including employment, investment, business start-ups and school results show that Middlesbrough's quality of life and prospects are improving."
Cllr Budd added: "We all know the town has a long way to go but everyone is working to make it a better place to live and work. We certainly won't let a single TV programme divert us from that job."
It is the third year in a row the town has made the “worst” top 10 list. Channel 4's property show Location, Location, Location says crime, health, education and other figures have been collated to work out a formula to rank areas nationwide.