Lambeth LBC’s chief executive Sean Harriss has resigned due to ill health.
Mr Harriss, who was appointed to the role at the London borough in March 2015, has been off work since June this year, the council said.
Lib Peck (Lab), Lambeth’s leader, said: “Sean was very committed to the role, and his enthusiastic personality meant that staff throughout the organisation will have fond memories of working with him.
“His resignation is a loss to Lambeth, especially given the amount of work the organisation is currently undertaking.”
The council has convened an appointments panel to seek an interim chief executive with its recommendations expected to be considered at the meeting of full council on October 18. Once an interim is appointed Lambeth intends to start work on appointing permanently to the post.
Mr Harriss was chief executive of Bolton MBC between 2007 and 2015.