The four are all social work staff involved in providing care for the elderly, and are members of the direct sales organisation Amway.
They are expected to appear at disciplinary hearings tomorrow to answer allegations that they placed undue pressure on junior staff to join the pyramid marketing organisation.
A spokesman said the council had set up a 'substantial fact-finding investigation' after several staff raised concerns with senior officers. This investigation was continuing, he said.
A confidential telephone help-line has been set up. On the details of the case, South Lanarkshire has said only that the staff had been suspended on charges relating to the council's code of conduct.
Three of the four managers involved are Matthew Monahan, Frances Morgan and Samuel McKay.
Part of the council's concern has been that heavy pressure may also have been put on social work clients to join Amway as distributors, so earning more money for the recruiter.
'Our belief is that this was not the case,' one source said. 'We were extremely concerned that it could have been because we are dealing with vulnerable people.' None of the managers involved was available for comment.